04 January 2023
Tiziana has announced that the Investigational New Drug (IND) application for milciclib in combination with gemcitabine for non-small cell lung cancer (NSCLC) has been filed.Read more
03 January 2023
29 December 2022
London, 29 December 2022 – Tiziana Life Sciences Ltd (“Tiziana”, NASDAQ: TLSA), a biotechnology company enabling breakthrough CNS immunomodulation approaches to enhance the functionality of Treg-based therapies, today announced its interim results for the six months ended 30 June 2022.
Our mission is to bring breakthrough therapies to patients with the aim of treating SPMS, Crohn's Disease, lung diseases and optimizing health outcomes.Learn more
Our major clinical assets are supported by extensive worldwide issued patents and pending patent applications covering composition of matter, formulation technologies, manufacturing processes and disease indications.
Foralumab is a fully human anti-CD3 monoclonal antibody (mAb) for treatment of Crohn’ s Disease and neurodegenerative indications.Learn more about Foralumab
We are developing a fully human monoclonal antibody (mAb) targeting the receptor for IL-6 as a potential treatment for lung diseases.Learn more about Anti IL-6R
Milciclib is the Company’s clinical candidate for the treatment in cancer indications. The company is exploring the combination of milciclib and gemcitibine in NSCLC patients with pan KRAS+ mutations.Learn more about Milciclib
Tiziana is currently conducting clinical development programs for Foralumab, Anti IL-6R and Milciclib
Tiziana reported positive clinical data in a Phase I clinical trial of nasally-dosed Foralumab in healthy subjects in collaboration with Dr. Howard Weiner at Brigham and Women’s Hospital in Boston. Phase 2 patient enrollment is expected to begin in 1H 2022 for nasally administered Foralumab for the treatment of Non-active SPMS.See more Foralumab clinical trials
Manufacturing of clinical supplies for a Phase 1 study is anticipated to be completed in 4Q 2022.
We are exploring a study to evaluate the combination of milciclib and gemcitabine in NSCLC subjects with associated pan KRAS-positive mutations.See more Milciclib clinical trials